3D Ultrasound Computer Tomography for Breast Cancer Diagnosis:

Current Status
 

Nicole V. Ruiter

Karlsruhe Institute for Technology, Karlsruhe, Germany

 

Early breast cancer diagnosis is still a major challenge. The standard screening methods often detect cancer in a state when metastases have already developed. The presence of metastases decreases the probability of survival significantly. A more sensitive tool for breast cancer diagnosis will lead to diagnoses in an earlier state, i.e. before metastases are generated.

 

We are developing a new imaging method for breast cancer diagnosis, ultrasound computer tomography (USCT), which allows recording of reproducible 3D images with high spatial resolution and tissue contrast. Additionally, quantitative measurements of physical parameters, such as sound speed and attenuation, which could be used to identify cancerous tissues, are possible.

 

Our first experimental 3D USCT showed that full 3D data acquisition is feasible with today's technology; if a sparse aperture may be accepted. The next question is the clinical relevance of such a device. To answer this question, we are currently building a second generation 3D USCT setup with the main aim to image volunteers.

 

In this talk the setups and the results of the 3D systems are presented. The challenges of building such a system and possible solutions are proposed. The currently applied reconstruction algorithms will be presented together with first 3D images and the optimized setup for the next system is discussed.